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Clopidogrel is indicated to reduce the rate of myocardial infarction MI and stroke in patients with non-ST-segment elevation ACS unstable anginaUA /non-ST-elevation myocardial infarctionNSTEMI including patients what is clopidogrel bisulfate 75 mg are to be managed medically and those who are to be managed with coronary revascularization.

Clopidogrel should be administered in conjunction with aspirin.In the CURE study, the combined incidence of cardiovascular death, nonfatal MI, or stroke, and the combined incidence of these 3 types of events plus refractory ischemia in the clopidogrel group were reduced compared with these outcomes in the placebo group. Clopidogrel therapy also was associated with reductions in the incidences of refractory or severe ischemia, heart failure, and during the initial period of hospitalization revascularization procedures.

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The observed risk of bleeding events with clopidogrel plus aspirin versus placebo plus aspirin by age category is provided in Table 1 and Table 2 for the CURE and COMMIT trials, respectively see Adverse Reactions 6.But the risk of bleeding exceeded the benefits in those with a plavix clopidogrel bisulfate of strokes or transient ischemic attacks fleeting, strokelike symptoms It had no advantage plavix clopidogrel bisulfate clopidogrel in two other groups with increased bleeding risk: people older than age 75 or weighing less than about plavix clopidogrel bisulfate pounds.

And those who needed coronary artery bypass surgery after the PCI had substantially higher risks with prasugrel than with the older drug.

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ABG or other surgical procedure.Myocardial infarction and stroke are medical emergencies. Therapy for the pregnant woman should not be withheld because of potential concerns regarding the effects of clopidogrel on the fetus.

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Acc.Consequently, a direct effect slight toxicity or an indirect effect low palatability cannot be excluded.

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