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|Trade names||Effexor, others |
|License data||US DailyMed: b23637e5-d37f-41b5-ba76-fc053e903bc2|
|Pregnancy category||AU: B2 US: C (Risk not ruled out)|
|Routes of administration||By mouth|
|ATC code||N06AX16 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Protein binding||27±2% (parent compound), 30±12% (active metabolite, desvenlafaxine) |
|Metabolism||Liver (~50% of the parent compound is metabolised on first pass through the liver)  |
|Elimination half-life||5±2 h (parent compound for immediate release preparations), 15±6 h (parent compound for extended release preparations), 11±2 h (active metabolite)  |
|Excretion||Kidney (87%; 5% as unchanged drug; 29% as desvenlafaxine and 53% as other metabolites)  |
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Memory loss is not as severe.Ann Intern Med. 66-167. PubMed Citation Full Text 12.
How to wean yourself off 37.5mg effexor?
It is generally recommended that individuals taking antidepressant medications also find a qualified therapist to speak with.Serotonin-norepinephrine reuptake inhibitors SNRIs may cause symptoms of sexual dysfunction see section 4.
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Continuous dopaminergic stimulation reduces risk of motor complications in parkinsonian primates.Cardio is key to the whole thing, and it sound like you know that. Not to mention the major supplemental depression fighting benefit of regular cardio.
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The VA/DoD guidelines specifically do not recommend benzodiazepines, tiagabine, guanfacine, valproate, or topiramate. None of these drugs has demonstrated evidence of benefit.For Depression: It changed my life.
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