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Fluoxetine (top), ( R )-fluoxetine (center), ( S )-fluoxetine (bottom)
Clinical data
Pronunciation/ f l u ˈ ɒ k s ə t iː n /
Trade namesProzac, Sarafem, Adofen, other
License dataUS   FDA: Fluoxetine
Pregnancy categoryAU: C US: C (Risk not ruled out)
Dependence liabilityPhysical: Low Psychological: Low
Addiction liabilityNone
Routes of administrationBy mouth
Drug classSelective serotonin reuptake inhibitor (SSRI) [1]
ATC codeN06AB03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability60–80% [1]
Protein binding94–95% [3]
MetabolismLiver (mostly CYP2D6-mediated) [2]
Metabolitesnorfluxotine, desmethylfluoxetine
Elimination half-life1–3 days (acute) 4–6 days (chronic) [2] [4]
ExcretionUrine (80%), faeces (15%) [2] [4]

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Fluoxetine is used to treat depression, panic attacks, obsessive compulsive disorder, a certain eating disorder (bulimia), and a severe form of premen.: fluoxetine 40 mg capsule | Kaiser Permanente

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Risk for autism spectrum disorders according to period of prenatal antidepressant exposure and JAMA Pediatrics. complaint - Consumer Product Safety Commission Maximum recommended dose is 60 mg/day. Children and adolescents aged 8 years and above moderate to severe major depressive episode Fluoxetine 60mg capsules are not licensed and are not appropriate for use in children or adolescents.

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I do not have the nightmares any longer, I do not actually think about the last, well I never attempt to think about just just just what took place. References | National Institute on Drug Abuse NIDA 6932 Fluoxetine is excreted in breast milk, avoid use when lactating. fluoxetine lowest dosage.

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Tambi n puede comunicarlos directamente a trav s del Sistema Espa ol de Farmacovigilancia de medicamentos de Uso Humano: ww.If you are just starting, be patient! I know that I am still not even feeling the full effects at this point, and that I will continue to have ups and downs, but already it has helped so much.

Does fluoxetine metabolize by cyp2c9?

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If you or someone else has accidentally ingested this medication call the National Capital Poison Center at. 22.Because of the possibility of developing potentially serious, sometimes fatal serotonin syndrome or NMS-like reactions, sibutramine no longer commercially available in the US should be used with caution in patients receiving fluoxetine.

What to know about taking fluoxetine?

Avoid combinations; the risk of the interaction outweighs the benefit.Having an anxiety disorder puts a child at risk for depression and drug abuse, and appears to continue into adulthood. There is very little information on anxiety medications for children.

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Compared to other SSRIs they have shorter half-lives and lower passage into milk.Therefore, fluoxetine should not be used in nursing women, and women should be advised to notify their physician if they plan to breast-feed. In addition, the slow elimination of fluoxetine and norfluoxetine from the body after discontinuance of the drug should be considered.

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There was no specific pattern of cardiovascular malformations observed in this trial.Elderly people may be at greater risk for this.

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Arlington, VA: APA Press; 2013. Keeton CP, Kolos AC, Walkup JT. Pediatric generalized anxiety disorder: epidemiology, diagnosis, and management.e-mail: m The funders had no role in the design, execution, or writing of the study.

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Of patients receiving fluoxetine therapy to date. nd in at least one patient undergoing electroconvulsive therapy ECT concomitantly.It is important to emphasize that prozac causes weight loss reported during therapy were not necessarily caused by it.

The prescriber should be aware that the figures in the tables and tabulations cannot be used to predict the incidence of side effects in the course of usual medical practice where patient characteristics and other factors differ from those that prevailed in the clinical trials.

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