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Sodium bicarbonate solution.There is a need to develop mitomycin ophthalmic injection therapies which combine efficacy with acceptable toxicity. The current 'gold standard' gemcitabine gives an objective response rate of the order of 20% and median survival up to 6 months.

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Extravasation may occur mitomycin eye injection or without an accompanying stinging or burning sensation and even if there is adequate blood mitomycin eye injection when the injection needle is aspirated. There have been reports of delayed erythema and/or ulceration occurring either at or distant from the injection site, weeks to months after Mitomycin for Injection USP, even when no obvious evidence of extravasation was observed during administration.Heating a chemotherapy solution and infusing it directly into the abdomen may kill more tumor cells.

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