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Clinical data
PronunciationParacetamol: / ˌ p ær ə ˈ s iː t ə m ɒ l / Acetaminophen: / ə ˌ s iː t ə ˈ m ɪ n ə f ɪ n / ( listen )
Trade namesTylenol, Panadol, others [2]
License dataUS   FDA: Acetaminophen
Pregnancy categoryAU: A US: C (Risk not ruled out) [1] Not tested but seems to be safe
Routes of administrationBy mouth, through the cheek, rectal, intravenous (IV)
ATC codeN02BE01 ( WHO )
Legal status
Legal statusAU: S4 (Rx), OTC, and unscheduled UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability63–89% [4] : 73
Protein binding10–25% [5]
MetabolismPredominantly in the liver [3]
MetabolitesAPAP gluc, APAP sulfate, APAP GSH, APAP cys, NAPQI [6]
Onset of actionPain relief onset by route: By mouth – 37 minutes [7] Buccal – 15 minutes [7] Intravenous – 8 minutes [7]
Elimination half-life1–4 hours [3]
ExcretionUrine (85–90%) [3]

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Ashley PF, Parekh S, Fences DR, Anand P, MacDonald LC 8 Extraordinary 2016 "Preoperative analgesics for panadol ultra discontinued pain relief in women and similarities histology ruined leader" PDF The Cochrane Database of Related Reviews 8 CD008392. doi.

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Most people tend to get enough vitamin C in their usual diet. Absorption of paracetamol following rectal administration of Panadol suppositories to postoperative children is slower and reduced as compared to oral therapy. Retrieved 23 February 2014 — panadol soluble indonesia. Sarg M, Ann D Gross, Altman R 2007 The Cancer Dictionary.

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Shriner K, Goetz MB "Magnificent hepatotoxicity in a variety majority panadol ultra discontinued acetaminophen and zidovudine. Am J Med. 94-623. Rumore MM, Blaiklock RG "All of age-dependent panadol ultra discontinued and metabolism on acetaminophen hepatotoxicity. J Pharm Sci. 203-724. Lee WM "Aunt progress: drug-induced hepatotoxicity.

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Do not take more than the recommended dose, as this may be panadol cold flu vapour release decongestant, including serious harm to your liver. Panadol Actifast contains a unique formulation which gets to the source of pain fast.The speed of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption reduced by cholestyramine or go to this site. he anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.

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The effectiveness of the antidote declines sharply after this time.Available at: ww. ayoclinic.

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Avoiding overdose: Acetaminophen is a frequent cause of accidental poisoning for infants and children. Keep the medication out of the reach of children, use an panadol cold and flu vapor release syringe to measure the dose, read the package carefully, and consult your pharmacist or doctor to confirm the best dose for your child.Children should not be given Panadol Advance 500 mg Tablets for more than 3 days without consulting a doctor.

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Retrieved 10 May 2014.The sinuses are four pairs of air-filled cavities behind your cheekbones and forehead. Their role is to ensure the air coming in through the nose is at the right temperature and humidity before it enters the lungs.

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Use only as directed on the label. For relief of pain and fever.GSK is committed to the effective collection and management of human panadol flu powder information relating to our products. If you panadol flu powder to report an adverse event or side effect with one of our products please send an email on m or call us at 2-21-111-475-725 between 9: 0AM and 5: 0PM on weekdays so we can give you more personalized attention.

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Opiate analgesics may interact with monoamine oxidase inhibitors MAOIs and result in serotonin syndrome.Tell your doctor if you are pregnant before using this medication.

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Ake this panadol flu powder by mouth as directed.However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling especially of the face/tongue/throat severe dizziness, trouble breathing.

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It contains Paracetamol which provides pain-relieving and fever-reducing actions, Phenylephrine Hydrochloride which is a decongestant to relieve panadol flu powder congestion, and Guaiphenesin which is an expectorant for chesty cough.Properly discard this product when it is expired or no longer needed.

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