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This deteriorating response is currently interpreted as a manifestation of the inability of the ever decreasing population of intact nigrostriatal neurons to synthesize and release adequate amounts of dopamine. MAO B inhibition may be selegiline hcl 5mg in this setting because, by blocking the catabolism of dopamine, it would increase the net amount of dopamine available i.If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

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Because Anipryl belongs to a class of drugs called Monoamine Oxidase Inhibitors MAOI it should not be given with antidepressants such as Prozac.2003 Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness.


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Curr Psychiatry Rep. Meyers BS, Jeste DV. Geriatric psychopharmacology: evolution of a discipline.jp. oudim, M. B. H. and Tipton, K. F. 2002 Rat striatal monoamine oxidase-B inhibition by l-deprenyl and rasagiline: its relationship to 2-phenylethylamine-induced stereotypy and Parkinson s disease.

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