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In some patients, concomitant use of these two drug classes can lower blood pressure significantly leading to symptomatic hypotension for example, fainting Patients should be stable on alpha-blocker therapy prior to initiating a PDE5 inhibitor.
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Primary efficacy assessment in all four major trials was by means of the Erectile Function EF Domain score of the validated International Index of Erectile Function IIEF Questionnaire and two questions from the Sexual Encounter Profile SEP dealing with the ability to achieve vaginal penetration SEP2 and the ability to maintain an erection long enough for successful intercourse SEP3 In the North American trial, LEVITRA significantly improved the rates of achieving an erection sufficient for penetration SEP2 at doses of 5 mg, snovitra levitra mg, and 20 mg compared to placebo.
nd 80% respectively, compared to a 52% response in the placebo group at 3 snovitra levitra p 0.LEVITRA has systemic vasodilatory properties that resulted in transient decreases in supine blood pressure in healthy volunteers snovitra levitra maximum decrease of 7 mmHg systolic and 8 mmHg diastolic see Clinical Pharmacology 12. While this normally would snovitra levitra expected to be of little consequence in most patients, prior to prescribing LEVITRA, physicians should carefully consider whether their patients with underlying cardiovascular disease could be affected adversely by such snovitra levitra effects.
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